| 960-1972 | Schooldays |
| 1972-1974 | Military Service (Bundeswehr) |
| 1974-1976 | Medical School, Universität Freiburg and Freie Universität Berlin |
| 1976-1980 | Medical School, Technische Universität München |
| 1980 | National Board Examination |
| 1981 | Thesis (‘Dr. Med’) : Fibrin glue application in liver parenchymal defects (Magna cum laude) |
| 1980-1982 | Resident, Department of Cardiovascular Surgery, German Heart Center Munich 1982 -1983 Fellowship, University of Chicago, Michael Reese Hospital |
| 1982-1983 | Fellowship, University of Chicago, Michael Reese Hospital |
| 1983-1984 | General Surgery, Kanonsspital Basel, Switzerland |
| 1985 | General Surgery, University Hospital Mainz |
| 1986-1992 | Department of Cardiothoracic and Vascular Surgery, University Hospital Mainz |
| 1992-1999 | Department of Cardiac Surgery, University Hospital Heidelberg |
| 1987 | German Board Certification for Thoracic and cardiovascular Surgery |
| 1987 | Consultant |
1991 1992 – 1999 1999 – 07/2019 | Ph. D. (‘Habilitation’) Vize Chairman, Dep. of Cardiac Surgery, University of Heidelberg Director, Dep. of Thoracic and Cardiovascular Surgery, University Hospital Essen |
| – | Member of the German Society for Surgery |
| – | Member of the German Society for Thoracic and Cardiovascular Surgery |
| – | Member of the German Society for Transplantation |
| – | Member of the European Association of Cardiothoracic Surgeons |
| – | Member of the Society of Thoracic Surgeons |
| – | Member of the American Society for Artificial Organs |
| – | Member of the American Association of Thoracic Surgery |
| 2001 | Fellow, the European Assosciation Thoracic & Cardiovascular Surgery (FETCS) |
| 2007 | First prize, Business Plan Competition, Spring 2007, Medical Businesses, State of North Rhine-Westfalia |
| 2009 | First prize, Innovation Competition of the State Baden-Württemberg 2009, The E-Vita open Hybrid graft |
| 2014 | EACTS/STS Award – Best Presentation |
| 2015-2019 | Multiple best presentations ESCVS, DGTHG |
| – | Complex caronary artery surgery |
| – | Ventricular Reconstructive Surgery |
| – | Transapical Aortic Valve Implantation |
| – | Implantable Assist Devices |
| – | Heart and Lung Transplantation |
| – | Surgery of Thoracic Aorta (including endovascular Therapies) |
| – | Endoscopic Valvular Surgery |
Jakob H, Campbell CD, Qiu ZK, Pick R, Replogle RL. Evaluation of fibrin sealing for cardiovascular sugery. Circulation 1987;70:I-138-146
Jakob H, Vahl C, Lange R, Micek M, Tanzeem A, Hagl S. Modified surgical concept for fulminant pulmonary embolism. Eur J Cardiothorac Surg 1995;9:557-561
Jakob H, Borneff-Lipp M, Bach A, von Pückler S, Windeler J, Sonntag H, Hagl S. The endogenous pathway is a major route for deep sternal wound infection. Eur J Cardiothorac Surg 2000;17(2): 54-60
Jakob H, Tsagakis K, Leyh R, Buck T, Herold U. Development of an integrated stent graft-dacron prosthesis for intended one-stage repair in complex thoracic aortic disease. Herz 2005;30(8):766-8
Thielmann M, Massoudy P, Neuhauser M, Tsagakis K, Marggraf G, Kamler M, Mann K, Erbel R., H. Jakob. Prognostic value of preoperative cardiac troponin I in patients undergoing emergency coronary artery bypass surgery with non-ST-elevation or ST-elevation acute coronary syndromes. Circulation. 2006;114:I448-53.
Jakob H, Tsagakis K, Tossios P, Massoudy P, Thielmann M, Buck T, Eggebrecht H, Kamler M.
Combining classic surgery with descending stentgrafting in acute DeBakey type I dissection.
Ann Thorac Surg 2008;86:95-101.Thielmann M, Kottenberg E, Kleinbongard P, Wendt D, Gedik NPasa S, Price V, Tsagakis K, Neuhäuser M, Peters J, Jakob H, Heusch G.
Heusch G, Musiolik J, Kottenberg E, Peters J, Jakob H, Thielmann M
STAT5 Activation and Cardioprotection by Remote Ischemic Preconditioning in Humans, Circ. 2012 110(1): 111-5
Jakob H, Dohle DS, Piotrowski J, Benedik J, Thielmann M, Marggraf G, Erbel R, Tsagakis K
Six-year experience with a hybrid stent graft prosthesis for extensive thoracic aortic disease: an interim balance.
Eur J Cardiothorac Surg. 2012 42(6): 1018-25
Grabenwöger M, Alfonso F, Bachet J, Bonser R, Czerny M, Eggebrecht H, Evangelista A, Fattori R, Jakob H, Lönn L, Nienaber CA, Rocchi G, Rousseau H, Thompson M, Weigang E, Erbel R
Thoracic Endovascular Aortic Repair (TEVAR) for the treatment of aortic diseases: a position statement from the European Association for Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC), in collaboration with the European Assoc
Eur Heart J. 2012 33(13): 1558-63
Wendt D, Pasa S, Kahlert P, Delaloye S, Al-Rashid F, Price V, Jánosi RA, Borenstein N, Behr L, Konorza T, Erbel R, Jakob H, Thielmann M
A New self-expandable transcatheter aortic valve for transapical implantation: feasibility in acute and chronic animal experiments.
Scand Cardiovasc J. 2013 47(3): 145-53
Yan TD, Tian DH, Lemaire SA, Hughes GC, Chen EP, Misfeld M, Griepp RB, Kazui T, Bannon PG, Coselli JS, Elefteriades JA, Kouchoukos NT, Underwood MJ, Mathew JP, Mohr FW, Oo A, Sundt TM, Bavaria JE, Di Bartolomeo R, Di Eusanio M, Trimarchi S, International Aortic Arch Surgery Study Group , Appoo J, Bavaria J, Chen E, Corvera J, Coselli J, Elefteriades J, Griepp R, Hughes C, Kouchoukos N, LeMaire S, Mathew J, Patel H, Pochettino A, Roselli E, Safi H, Spielvogel D, Sundt T, Xydas S, Bartolomeo R, Carrel T, Della A, Di Eusanio M, Dossche K, Grabenwoeger M, Harringer W, Haverich A, Jakob H, Mascaro J, Misfeld M, Mohr FW, Oo A, Sinatra R, Steinbruchel D, Trimarchi S, Asai T, Bannon P, Kazui T, Matalanis G, Numata S, Okita Y, Sun LZ, Tabata M, Underwood M, Wang C, Yan T
Standardizing clinical end points in aortic arch surgery: a consensus statement from the International Aortic Arch Surgery Study Group.
Circulation. 2014 129(15): 1610-6
Wendt D, Thielmann M, Plicht B, Aßmann J, Price V, Neuhäuser M, Jakob H
The new St Jude Trifecta versus Carpentier-Edwards Perimount Magna and Magna Ease aortic bioprosthesis: is there a hemodynamic superiority?
J Thorac Cardiovasc Surg. 2014 147(5): 1553-60
Wendt D, Kahlert P, Pasa S, El-Chilali K, Al-Rashid F, Tsagakis K, Dohle DS, Erbel R, Jakob H, Thielmann M
Transapical transcatheter aortic valve for severe aortic regurgitation: expanding the limits.
JACC Cardiovasc Interv.
2014 7(10): 1159-67
Dohle DS, Tsagakis K, Janosi RA, Benedik J, Kühl H, Penkova L, Stebner F, Wendt D, Jakob H. Aortic remodelling in aortic dissection after frozen elephant trunk+ Eur J Cardiothorac Surg. 2015 49(1):111-7
Weiss G, Tsagakis K, Jakob H, Di Bartolomeo R, Pacini D, Barberio G, Mascaro J, Mestres CA, Sioris T, Grabenwoger M
The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience
Eur J Cardiothorac Surg. 2015 47(1): 106-14
Leontyev S, Tsagakis K, Pacini D, Di Bartolomeo R, Mohr FW, Weiss G, Grabenwoeger M, Mascaro JG, Iafrancesco M, Franke UF, Göbel N, Sioris T, Widenka K, Mestres CA, Jakob H
Impact of clinical factors and surgical techniques on early outcome of patients treated with frozen elephant trunk technique by using EVITA open stent-graft: results of a multicentre study+.
Eur J Cardiothorac Surg. 2016 49(2): 660-6
Leontyev S, Tsagakis K, Pacini D, Di Bartolomeo R, Mohr FW, Weiss G, Grabenwoeger M, Mascaro JG, Iafrancesco M, Franke UF, Göbel N, Sioris T, Widenka K, Mestres CA, Jakob H
Impact of clinical factors and surgical techniques on early outcome of patients treated with frozen elephant trunk technique by using EVITA open stent-graft: results of a multicentre study+.
Eur J Cardiothorac Surg.
2016
49(2): 660-6
Jánosi RA, Gorla R, Tsagakis K, Kahlert P, Horacek M, Bruckschen F, Dohle DS, Jakob H, Schlosser T, Eggebrecht H, Bossone E, Erbel R
Thoracic Endovascular Repair of Complicated Penetrating Aortic Ulcer: An 11-Year Single-Center Experience.
J Endovasc Ther.2016 23(1): 150-9
Tsagakis K, Benedik J, Jakob H
Aortic root endoscopy. J Thorac Cardiovasc Surg. 2016
152(2): 639-40
Jakob H, et al.
Long term experience with the E-vita open hybrid graft in complex thoracic aortic disease
Eur J Cardiothorac Surg. 2016 Epub ahead of print
http://www.ncbi.nlm.nih.gov/pubmed/?term=Jakob+H%5BAuthor%5D
| FREEDOM-Trial: Comparison of Two Treatments for Multivessel Coronary Artery Disease in Individuals With Diabetes | SI | NHLBI | 2004-2009 |
| PARTNER TRIAL: Placement of AoRTic TraNscathetER Valve Trial | PI | NCT00530894 | 2007-2012 |
| SOURCE-I Registry: Aortic Bioprosthesis Multi-region Outcome Registry I | PI | 2007-2012 | |
| SOURCE-II Registry: Aortic Bioprosthesis Multi-region Outcome Registry II | PI | 2010-2015 | |
| SOURCE XT Registry: SAPIEN XT™ Aortic Bioprosthesis Multi-region Outcome Registry | PI | NCT01238497 | 2011-2015 |
| Prevail-TA Study: Placement of Aortic Balloon Expandable Transcatheter Valves Trial (TransApical) | PI | NCT00820599 | 2009-2014 |
| ACURATE-TA: First-in-man study | PI | 2010-2015 | |
| ACURATE-TA: Pilot Study | PI | 2010-2015 | |
| EXCEL Trial: Evaluation of XIENCE PRIME™ or XIENCE V® versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization | PI | NCT01205789 | 2011-2016 |
| Re-ALIGN I&II: Evaluation of the Long Term Safety of the Use of Dabigatran Etexilate in Patients With a Bileaflet Mechanical Heart Valve | PI | NCT01505881 | 2012-2018 |
| Trifecta Durability Study Evaluation of the long-term durability of the Trifecta™ valve | PI | NCT01256710 | 2011-2021 |
| ROUTE Utilisation of the Transaortic (Tao) TAVI Approach Using the Edwards Sapien XT Valve | PI | NCT01991431 | 2013-2018 |
| EASE-ITBalloon Expandable Transcatheter Aortic Valve Implantation Without Predilation of the Aortic Valve (EASE-IT) | PI | NCT02127580 | 2013-2018 |
| SAPIEN 3 Safety and Performance Study of the Edwards SAPIEN 3 Transcatheter Heart Valve/ The SAPIEN 3 Study (SAPIEN3) | PI | NCT01808287 | 2013-2018 |
| VEST III Preventive treatment of saphenous vein grafts in patients who undergo coronary artery bypass grafting procedure | PI | – | 2015-2017 |
| QUARK – QPI-1002 A Study to Evaluate Efficacy and Safety of QPI-1002 for Prevention of Acute Kidney Injury Following Cardiac Surgery | PI | NCT 02610283 | 2016-2017 |
| CABY1 Study Selective depletion of the C-reactive protein by means of therapeutic CRP apheresis to reduce myocardial damage after coronary bypass surgery | PI | DRKS00013012 | 2017-2019 |
| 2012 | Aortic Live 1, Essen |
| 2014 | Aortic Live 2, Essen |
| 2016 | Aortic Live 3, Essen |
| 2017 | Aortic Live 4, Hamburg |
| 2018 | Aortic Live 5, Essen |
